Gene description for ZCCHC14
Gene name zinc finger, CCHC domain containing 14
Gene symbol ZCCHC14
Other names/aliases BDG-29
BDG29
Species Homo sapiens
 Database cross references - ZCCHC14
ExoCarta ExoCarta_23174
Entrez Gene 23174
HGNC 24134
UniProt Q8WYQ9  
 ZCCHC14 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for ZCCHC14
Molecular Function
    zinc ion binding GO:0008270 IEA
    nucleic acid binding GO:0003676 IEA
    phosphatidylinositol binding GO:0035091 IEA
 Experiment description of studies that identified ZCCHC14 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for ZCCHC14
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NFIC  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ZCCHC14 is involved
No pathways found





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