Experiment description of studies that identified PLCL2 in exosomes

1 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for PLCL2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SLC35F5   Affinity Capture-MS Homo sapiens 2 DSCAML1   Two-hybrid Homo sapiens 3 NXF1 10482 Affinity Capture-RNA Homo sapiens 4 PPP1CA 5499 Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 PPP1CC 5501 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 KRAS 3845 Proximity Label-MS Homo sapiens 7 PPIL3 53938 Affinity Capture-MS Homo sapiens 8 PPP1CB 5500 Affinity Capture-MS Homo sapiens 9 CASP1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 10 SHOC2 8036 Affinity Capture-MS Homo sapiens 11 C11orf52 91894 Proximity Label-MS Homo sapiens 12 MTHFS 10588 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens View the network

Pathways in which PLCL2 is involved

No pathways found