Gene description for HID1
Gene name HID1 domain containing
Gene symbol HID1
Other names/aliases C17orf28
Species Homo sapiens
 Database cross references - HID1
ExoCarta ExoCarta_283987
Entrez Gene 283987
HGNC 15736
MIM 605752
UniProt Q8IV36  
 HID1 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for HID1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    intracellular protein transport GO:0006886 IDA
    response to brefeldin A GO:0031001 IDA
Subcellular Localization
    extrinsic component of Golgi membrane GO:0090498 IDA
    Golgi trans cisterna GO:0000138 IDA
    extracellular exosome GO:0070062 IDA
    Golgi medial cisterna GO:0005797 IDA
    Golgi apparatus GO:0005794 IDA
    cytoplasm GO:0005737 IDA
    cytoplasmic microtubule GO:0005881 IDA
 Experiment description of studies that identified HID1 in exosomes
Experiment ID 191
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HID1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CBS 875
Two-hybrid Homo sapiens
2 RCN3  
Two-hybrid Homo sapiens
3 KIAA1446  
Two-hybrid Homo sapiens
4 RBBP8  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which HID1 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here