Gene description for Prosbeta2
Gene name Proteasome beta2 subunit
Gene symbol Prosbeta2
Other names/aliases 3329
Beta-2
CG3329
DTS-7
DTS7
DmelCG3329
Dts7
PROSbeta2
Prosbeta
Prosbeta 2
anon-EST:fe1E6
anon-EST:fe1G6
b2
beta 2
beta2
beta2_dm
l(3)DTS7
prosbeta
prosbeta2
Species Drosophila melanogaster
 Database cross references - Prosbeta2
ExoCarta ExoCarta_39628
Entrez Gene 39628
 Prosbeta2 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Prosbeta2
Molecular Function
    threonine-type endopeptidase activity GO:0004298 IEA
    endopeptidase activity GO:0004175 ISS
Biological Process
    cellular response to DNA damage stimulus GO:0006974 IMP
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 ISS
Subcellular Localization
    proteasome complex GO:0000502 IDA
    proteasome core complex, beta-subunit complex GO:0019774 ISS
    proteasome core complex GO:0005839 IDA
 Experiment description of studies that identified Prosbeta2 in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Prosbeta2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Prosbeta2 is involved
No pathways found





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