Gene description for SPATA7
Gene name spermatogenesis associated 7
Gene symbol SPATA7
Other names/aliases HEL-S-296
HSD-3.1
HSD3
LCA3
Species Homo sapiens
 Database cross references - SPATA7
ExoCarta ExoCarta_55812
Entrez Gene 55812
HGNC 20423
MIM 609868
UniProt Q9P0W8  
 SPATA7 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for SPATA7
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    photoreceptor cell maintenance GO:0045494 ISS
    protein localization to photoreceptor connecting cilium GO:1903621 ISS
    visual perception GO:0007601 IEA
    protein localization to photoreceptor outer segment GO:1903546 ISS
    response to stimulus GO:0050896 IEA
Subcellular Localization
    photoreceptor connecting cilium GO:0032391 ISS
    ciliary basal body GO:0036064 IDA
    microtubule cytoskeleton GO:0015630 IDA
    axoneme GO:0005930 IDA
 Experiment description of studies that identified SPATA7 in exosomes
1
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SPATA7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SPATA7 is involved
No pathways found





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