Gene description for EEPD1
Gene name endonuclease/exonuclease/phosphatase family domain containing 1
Gene symbol EEPD1
Other names/aliases HSPC107
Species Homo sapiens
 Database cross references - EEPD1
ExoCarta ExoCarta_80820
Entrez Gene 80820
HGNC 22223
UniProt Q7L9B9  
 EEPD1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for EEPD1
Molecular Function
    DNA binding GO:0003677 IEA
Biological Process
    DNA repair GO:0006281 IEA
 Experiment description of studies that identified EEPD1 in exosomes
1
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for EEPD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which EEPD1 is involved
No pathways found





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