Gene description for PTGS1
Gene name	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Gene symbol	PTGS1
Other names/aliases	COX1 COX3 PCOX1 PES-1 PGG/HS PGHS-1 PGHS1 PHS1 PTGHS
Species	Homo sapiens
Database cross references - PTGS1
ExoCarta	ExoCarta_5742
Entrez Gene	5742
HGNC	9604
MIM	176805
UniProt	P23219
PTGS1 identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for PTGS1

Molecular Function     heme binding GO:0020037 IEA     prostaglandin-endoperoxide synthase activity GO:0004666 TAS     metal ion binding GO:0046872 IEA     dioxygenase activity GO:0051213 IEA     peroxidase activity GO:0004601 TAS Biological Process     response to oxidative stress GO:0006979 IEA     inflammatory response GO:0006954 IEA     small molecule metabolic process GO:0044281 TAS     regulation of cell proliferation GO:0042127 IEA     prostaglandin biosynthetic process GO:0001516 ISS     oxidation-reduction process GO:0055114 IEA     cyclooxygenase pathway GO:0019371 TAS     lipid metabolic process GO:0006629 NAS     xenobiotic metabolic process GO:0006805 TAS     regulation of blood pressure GO:0008217 ISS     arachidonic acid metabolic process GO:0019369 TAS Subcellular Localization     photoreceptor outer segment GO:0001750 IEA     endoplasmic reticulum membrane GO:0005789 TAS     cytoplasm GO:0005737 ISS     extracellular exosome GO:0070062 IDA     nucleus GO:0005634 ISS     intracellular membrane-bounded organelle GO:0043231 ISS