Gene description for KIAA1324
Gene name KIAA1324
Gene symbol KIAA1324
Other names/aliases EIG121
Species Homo sapiens
 Database cross references - KIAA1324
ExoCarta ExoCarta_57535
Entrez Gene 57535
HGNC 29618
MIM 611298
UniProt Q6UXG2  
 KIAA1324 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for KIAA1324
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    macroautophagy GO:0016236 IMP
    positive regulation of autophagosome assembly GO:2000786 IMP
    positive regulation of vacuole organization GO:0044090 IMP
    negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 IMP
    cellular response to starvation GO:0009267 IMP
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    late endosome membrane GO:0031902 IEA
    lysosomal membrane GO:0005765 IEA
    trans-Golgi network GO:0005802 IDA
    lysosome GO:0005764 IDA
    integral component of plasma membrane GO:0005887 IDA
    late endosome GO:0005770 IDA
 Experiment description of studies that identified KIAA1324 in exosomes
1
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for KIAA1324
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which KIAA1324 is involved
No pathways found





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