Gene description for KIAA1324
Gene name KIAA1324
Gene symbol KIAA1324
Other names/aliases EIG121
Species Homo sapiens
 Database cross references - KIAA1324
ExoCarta ExoCarta_57535
Vesiclepedia VP_57535
Entrez Gene 57535
HGNC 29618
MIM 611298
UniProt Q6UXG2  
 KIAA1324 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for KIAA1324
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
Biological Process
    autophagosome assembly GO:0000045 IBA
    autophagosome assembly GO:0000045 IMP
    cellular response to starvation GO:0009267 IMP
    positive regulation of vacuole organization GO:0044090 IBA
    positive regulation of vacuole organization GO:0044090 IMP
    positive regulation of autophagosome assembly GO:2000786 IMP
Subcellular Localization
    lysosome GO:0005764 IBA
    lysosome GO:0005764 IDA
    lysosomal membrane GO:0005765 IEA
    late endosome GO:0005770 IBA
    late endosome GO:0005770 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
    trans-Golgi network GO:0005802 IBA
    trans-Golgi network GO:0005802 IDA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    late endosome membrane GO:0031902 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified KIAA1324 in exosomes
1
Experiment ID 66
MISEV standards
IEM
Biophysical techniques
TSG101|Alix|CD63|CD81
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for KIAA1324
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CIB1 10519
Two-hybrid Homo sapiens
2 IQCB1  
Affinity Capture-MS Homo sapiens
3 DCUN1D5 84259
Affinity Capture-MS Homo sapiens
4 OSBPL3 26031
Affinity Capture-MS Homo sapiens
5 TMEM131  
Affinity Capture-MS Homo sapiens
6 KLHL41 10324
Affinity Capture-MS Homo sapiens
7 TAF1A  
Affinity Capture-MS Homo sapiens
8 TRIM55  
Two-hybrid Homo sapiens
9 TAF6L 10629
Affinity Capture-MS Homo sapiens
10 TRIM63  
Two-hybrid Homo sapiens
11 DDX58 23586
Affinity Capture-RNA Homo sapiens
View the network image/svg+xml
 Pathways in which KIAA1324 is involved
No pathways found





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