Gene description for CCDC134
Gene name coiled-coil domain containing 134
Gene symbol CCDC134
Other names/aliases -
Species Homo sapiens
 Database cross references - CCDC134
ExoCarta ExoCarta_79879
Entrez Gene 79879
HGNC 26185
UniProt Q9H6E4  
 CCDC134 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for CCDC134
Subcellular Localization
    membrane GO:0016020 IDA
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified CCDC134 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for CCDC134
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CCDC134 is involved
No pathways found





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