Gene description for FAM117A
Gene name family with sequence similarity 117, member A
Gene symbol FAM117A
Other names/aliases -
Species Homo sapiens
 Database cross references - FAM117A
ExoCarta ExoCarta_81558
Vesiclepedia VP_81558
Entrez Gene 81558
HGNC 24179
UniProt Q9C073  
 FAM117A identified in sEVs derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for FAM117A
 Experiment description of studies that identified FAM117A in sEVs
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for FAM117A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 YWHAH 7533
Affinity Capture-MS Homo sapiens
2 ZAR1L  
Affinity Capture-MS Homo sapiens
3 YWHAQ 10971
Affinity Capture-MS Homo sapiens
4 YWHAG 7532
Affinity Capture-MS Homo sapiens
5 PICK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 AKR7L 246181
Affinity Capture-MS Homo sapiens
7 DYNLL2 140735
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 DYRK1A 1859
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 DYNLL1 8655
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 HMBOX1  
Affinity Capture-MS Homo sapiens
11 DYRK1B  
Affinity Capture-MS Homo sapiens
12 YWHAB 7529
Affinity Capture-MS Homo sapiens
13 COBLL1 22837
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FAM117A is involved
No pathways found





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