Experiment description of studies that identified MKRN2 in sEVs

1 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

Protein-protein interactions for MKRN2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 NUPL2 11097 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 RIMS2   Affinity Capture-RNA Homo sapiens 3 VPS35 55737 Affinity Capture-RNA Homo sapiens 4 HNRNPC 3183 Affinity Capture-MS Homo sapiens 5 MIB1 57534 Affinity Capture-RNA Homo sapiens 6 HDAC4   Affinity Capture-RNA Homo sapiens 7 DPYSL2 1808 Affinity Capture-RNA Homo sapiens 8 NOTCH3 4854 Affinity Capture-RNA Homo sapiens 9 GART 2618 Affinity Capture-RNA Homo sapiens 10 CASP3 836 Affinity Capture-RNA Homo sapiens 11 NFIB   Affinity Capture-RNA Homo sapiens 12 BCLAF1 9774 Affinity Capture-MS Homo sapiens 13 TRNP1   Affinity Capture-RNA Homo sapiens 14 MTOR 2475 Affinity Capture-RNA Homo sapiens 15 TOP2B 7155 Affinity Capture-RNA Homo sapiens 16 CTBP2 1488 Affinity Capture-RNA Homo sapiens 17 FMR1 2332 Affinity Capture-MS Homo sapiens Affinity Capture-RNA Homo sapiens 18 PARD3 56288 Affinity Capture-RNA Homo sapiens 19 E2F1 1869 Affinity Capture-RNA Homo sapiens 20 ZC3H14   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 21 UBA1 7317 Affinity Capture-MS Homo sapiens 22 PAX2   Affinity Capture-RNA Homo sapiens 23 DAB1 1600 Affinity Capture-RNA Homo sapiens 24 ODF2 4957 Affinity Capture-RNA Homo sapiens 25 IGF2BP1 10642 Affinity Capture-RNA Homo sapiens 26 SEMA6D   Affinity Capture-RNA Homo sapiens 27 HNRNPCL1 343069 Affinity Capture-MS Homo sapiens 28 SLIT2 9353 Affinity Capture-RNA Homo sapiens 29 BMPR1A 657 Affinity Capture-RNA Homo sapiens 30 SIX1   Affinity Capture-RNA Homo sapiens 31 TAF1   Affinity Capture-RNA Homo sapiens 32 SEMA3A   Affinity Capture-RNA Homo sapiens 33 RTN4 57142 Affinity Capture-RNA Homo sapiens 34 VASP 7408 Affinity Capture-RNA Homo sapiens 35 APP 351 Affinity Capture-RNA Homo sapiens 36 WDR36 134430 Affinity Capture-RNA Homo sapiens 37 SEMA4D   Affinity Capture-RNA Homo sapiens 38 FGFR3 2261 Affinity Capture-RNA Homo sapiens 39 HNRNPUL2 221092 Affinity Capture-MS Homo sapiens 40 EPHA8   Affinity Capture-RNA Homo sapiens 41 DLL1   Affinity Capture-RNA Homo sapiens 42 TOP2A 7153 Affinity Capture-MS Homo sapiens 43 RPS20 6224 Proximity Label-MS Homo sapiens 44 IGF2BP3 10643 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Biochemical Activity Homo sapiens 45 SNRNP70 6625 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 46 NEURL1   Affinity Capture-RNA Homo sapiens 47 ID4   Affinity Capture-RNA Homo sapiens 48 SEMA6A   Affinity Capture-RNA Homo sapiens 49 APAF1 317 Co-fractionation Homo sapiens 50 CEMIP 57214 Affinity Capture-MS Homo sapiens 51 UBE2K 3093 Two-hybrid Homo sapiens 52 DLX2   Affinity Capture-RNA Homo sapiens 53 SIRT6   Affinity Capture-RNA Homo sapiens 54 TM9SF4 9777 Affinity Capture-MS Homo sapiens 55 UBE2L3 7332 Reconstituted Complex Homo sapiens 56 NEDD4L 23327 Affinity Capture-RNA Homo sapiens 57 HIBCH 26275 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 58 KHDRBS1 10657 Affinity Capture-MS Homo sapiens 59 UNC5C   Affinity Capture-RNA Homo sapiens 60 THRAP3 9967 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 61 SRSF3 6428 Affinity Capture-MS Homo sapiens 62 BMPR1B 658 Affinity Capture-RNA Homo sapiens 63 TULP3 7289 Affinity Capture-RNA Homo sapiens 64 ATRX 546 Affinity Capture-RNA Homo sapiens 65 CDT1   Affinity Capture-RNA Homo sapiens 66 ATP6V0D1 9114 Affinity Capture-RNA Homo sapiens 67 UBB 7314 Affinity Capture-RNA Homo sapiens 68 FZD3   Affinity Capture-RNA Homo sapiens 69 MYCN   Affinity Capture-MS Homo sapiens 70 FOXP2 93986 Affinity Capture-RNA Homo sapiens 71 SEMA4F   Affinity Capture-RNA Homo sapiens 72 ERBB2 2064 Affinity Capture-RNA Homo sapiens 73 FGFR1 2260 Affinity Capture-RNA Homo sapiens 74 KIF3A 11127 Affinity Capture-RNA Homo sapiens 75 PABPC4 8761 Affinity Capture-MS Homo sapiens 76 WNT11 7481 Affinity Capture-RNA Homo sapiens 77 PROX1   Affinity Capture-RNA Homo sapiens 78 LARP4B 23185 Affinity Capture-MS Homo sapiens 79 NOTCH2 4853 Affinity Capture-RNA Homo sapiens 80 FAS 355 Proximity Label-MS Homo sapiens 81 ATXN2 6311 Affinity Capture-MS Homo sapiens 82 BRIX1 55299 Affinity Capture-MS Homo sapiens 83 CCND1 595 Affinity Capture-RNA Homo sapiens 84 BSG 682 Affinity Capture-RNA Homo sapiens 85 LRP8 7804 Affinity Capture-RNA Homo sapiens 86 RHOA 387 Affinity Capture-RNA Homo sapiens 87 SEMA6C   Affinity Capture-RNA Homo sapiens 88 ZIC2   Affinity Capture-RNA Homo sapiens 89 FOXC1   Affinity Capture-RNA Homo sapiens 90 PKM 5315 Affinity Capture-RNA Homo sapiens 91 RAB8A 4218 Affinity Capture-RNA Homo sapiens 92 ITGA6 3655 Affinity Capture-RNA Homo sapiens 93 RB1CC1 9821 Affinity Capture-MS Homo sapiens 94 PARK2   Affinity Capture-MS Homo sapiens 95 UBE2D4   Two-hybrid Homo sapiens 96 MAP1B 4131 Affinity Capture-RNA Homo sapiens 97 STIL   Affinity Capture-RNA Homo sapiens 98 WNT3   Affinity Capture-RNA Homo sapiens 99 ERCC6   Affinity Capture-RNA Homo sapiens 100 RBM4B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 101 PLD1 5337 Affinity Capture-RNA Homo sapiens 102 ATP2B1 490 Affinity Capture-RNA Homo sapiens 103 SRRT 51593 Affinity Capture-RNA Homo sapiens 104 SDK1 221935 Affinity Capture-RNA Homo sapiens 105 BVES   Affinity Capture-RNA Homo sapiens 106 DTNBP1   Affinity Capture-RNA Homo sapiens 107 TBC1D32 221322 Proximity Label-MS Homo sapiens 108 CCNB1 891 Affinity Capture-RNA Homo sapiens 109 PABPC1 26986 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 110 CARM1 10498 Affinity Capture-RNA Homo sapiens 111 FYN 2534 Affinity Capture-RNA Homo sapiens 112 C9orf41   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 113 MYH9 4627 Affinity Capture-MS Homo sapiens 114 GDF11 10220 Affinity Capture-RNA Homo sapiens 115 RBMS2 5939 Affinity Capture-MS Homo sapiens 116 PDE4D   Affinity Capture-RNA Homo sapiens 117 CDH4 1002 Affinity Capture-RNA Homo sapiens 118 GLI3 2737 Affinity Capture-RNA Homo sapiens 119 CNTN1 1272 Affinity Capture-RNA Homo sapiens 120 WNT5A 7474 Affinity Capture-RNA Homo sapiens 121 PLAG1   Affinity Capture-RNA Homo sapiens 122 LUC7L2 51631 Affinity Capture-MS Homo sapiens 123 NCS1 23413 Affinity Capture-RNA Homo sapiens 124 ALYREF 10189 Affinity Capture-MS Homo sapiens 125 MYH10 4628 Affinity Capture-MS Homo sapiens 126 PABPN1 8106 Affinity Capture-MS Homo sapiens 127 SDCCAG8   Affinity Capture-RNA Homo sapiens 128 MNAT1   Affinity Capture-RNA Homo sapiens 129 IARS 3376 Affinity Capture-MS Homo sapiens 130 PTPRA 5786 Affinity Capture-RNA Homo sapiens 131 NUMB 8650 Affinity Capture-RNA Homo sapiens 132 DBN1 1627 Affinity Capture-RNA Homo sapiens 133 GLTSCR2   Affinity Capture-MS Homo sapiens 134 HIF1A 3091 Affinity Capture-RNA Homo sapiens 135 GLI2   Affinity Capture-RNA Homo sapiens 136 EML1 2009 Affinity Capture-RNA Homo sapiens 137 LARP1 23367 Affinity Capture-MS Homo sapiens 138 ELAVL2 1993 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 139 P2RX4 5025 Affinity Capture-RNA Homo sapiens 140 HNRNPDL 9987 Affinity Capture-MS Homo sapiens 141 PAIP2B   Affinity Capture-MS Homo sapiens 142 FOXO6   Affinity Capture-RNA Homo sapiens 143 ACAT1 38 Affinity Capture-RNA Homo sapiens 144 TMEM30A 55754 Affinity Capture-RNA Homo sapiens 145 BAX 581 Affinity Capture-RNA Homo sapiens 146 C11orf57   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 147 XPO1 7514 Affinity Capture-MS Homo sapiens 148 CASZ1   Affinity Capture-RNA Homo sapiens 149 GLE1 2733 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 150 ROBO1 6091 Affinity Capture-RNA Homo sapiens 151 SARM1 23098 Affinity Capture-RNA Homo sapiens 152 PLRG1 5356 Affinity Capture-MS Homo sapiens 153 CTNNB1 1499 Affinity Capture-RNA Homo sapiens 154 PARP12 64761 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 155 DLG1 1739 Affinity Capture-RNA Homo sapiens 156 SUN1 23353 Affinity Capture-RNA Homo sapiens 157 LIMK1 3984 Affinity Capture-RNA Homo sapiens 158 SEMA3D   Affinity Capture-RNA Homo sapiens 159 TRIO 7204 Affinity Capture-RNA Homo sapiens 160 CUL3 8452 Affinity Capture-MS Homo sapiens 161 MYO7A 4647 Affinity Capture-RNA Homo sapiens 162 FZD1 8321 Affinity Capture-RNA Homo sapiens 163 MAGI2   Affinity Capture-RNA Homo sapiens 164 CLN5   Affinity Capture-RNA Homo sapiens 165 ARF6 382 Affinity Capture-RNA Homo sapiens 166 SYNE2 23224 Affinity Capture-RNA Homo sapiens 167 EPRS 2058 Affinity Capture-MS Homo sapiens 168 CEP290   Affinity Capture-RNA Homo sapiens 169 ZC3H11A   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 170 LARS 51520 Affinity Capture-MS Homo sapiens 171 HNRNPCL2 440563 Affinity Capture-MS Homo sapiens 172 DSCAML1   Affinity Capture-RNA Homo sapiens 173 NXF1 10482 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 174 CDC42 998 Affinity Capture-RNA Homo sapiens 175 EPHA7 2045 Affinity Capture-RNA Homo sapiens 176 PITPNA 5306 Affinity Capture-RNA Homo sapiens 177 HES4   Affinity Capture-RNA Homo sapiens 178 PRR3   Affinity Capture-MS Homo sapiens 179 EXT1 2131 Affinity Capture-RNA Homo sapiens 180 PRPF19 27339 Affinity Capture-MS Homo sapiens 181 MYC   Affinity Capture-RNA Homo sapiens 182 ZC3H18   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 183 EGFR 1956 Affinity Capture-RNA Homo sapiens 184 PABPC5 140886 Affinity Capture-MS Homo sapiens 185 EHMT2 10919 Affinity Capture-RNA Homo sapiens 186 TRA2A 29896 Affinity Capture-MS Homo sapiens 187 PABPN1L   Affinity Capture-MS Homo sapiens 188 OPA1 4976 Affinity Capture-RNA Homo sapiens 189 NRCAM   Affinity Capture-RNA Homo sapiens 190 RHOB 388 Affinity Capture-RNA Homo sapiens 191 FYTTD1   Affinity Capture-MS Homo sapiens 192 EN2   Affinity Capture-RNA Homo sapiens 193 S1PR1 1901 Affinity Capture-RNA Homo sapiens 194 CYFIP2 26999 Affinity Capture-RNA Homo sapiens 195 ASAP1 50807 Affinity Capture-RNA Homo sapiens 196 EPHB3 2049 Affinity Capture-RNA Homo sapiens 197 ARL13B 200894 Affinity Capture-RNA Homo sapiens 198 CYFIP1 23191 Affinity Capture-RNA Homo sapiens 199 RAE1 8480 Affinity Capture-MS Homo sapiens 200 SLIT1 6585 Affinity Capture-RNA Homo sapiens 201 CHD7   Affinity Capture-RNA Homo sapiens 202 UBE2D1 7321 Two-hybrid Homo sapiens 203 PAIP1 10605 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 204 TBX3 6926 Affinity Capture-RNA Homo sapiens 205 PPT1 5538 Affinity Capture-RNA Homo sapiens 206 LAMB1 3912 Affinity Capture-RNA Homo sapiens 207 ADCY1 107 Affinity Capture-RNA Homo sapiens 208 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 209 MKRN1 23608 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 210 CCND2   Affinity Capture-RNA Homo sapiens 211 PARP1 142 Proximity Label-MS Homo sapiens Co-fractionation Homo sapiens 212 CASP2   Affinity Capture-RNA Homo sapiens 213 PANK2 80025 Affinity Capture-RNA Homo sapiens 214 ZFC3H1 196441 Affinity Capture-MS Homo sapiens 215 AHI1   Affinity Capture-RNA Homo sapiens 216 IFT20 90410 Affinity Capture-RNA Homo sapiens 217 TP53 7157 Affinity Capture-RNA Homo sapiens 218 SATB2   Affinity Capture-RNA Homo sapiens 219 TGIF2   Affinity Capture-RNA Homo sapiens 220 MACF1 23499 Affinity Capture-RNA Homo sapiens 221 RBPJ 3516 Affinity Capture-RNA Homo sapiens 222 SYNJ1 8867 Affinity Capture-RNA Homo sapiens 223 WNT10B 7480 Affinity Capture-RNA Homo sapiens 224 APOBEC3D   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 225 LONP1 9361 Co-fractionation Homo sapiens 226 HDAC6 10013 Affinity Capture-RNA Homo sapiens 227 EPHA4 2043 Affinity Capture-RNA Homo sapiens 228 IRS2 8660 Affinity Capture-RNA Homo sapiens 229 TYRO3 7301 Affinity Capture-RNA Homo sapiens 230 CASK 8573 Affinity Capture-RNA Homo sapiens 231 MKRN3   Affinity Capture-MS Homo sapiens 232 PTBP3 9991 Affinity Capture-MS Homo sapiens 233 HDAC1 3065 Affinity Capture-RNA Homo sapiens 234 POU4F1   Affinity Capture-RNA Homo sapiens 235 CREB1   Affinity Capture-RNA Homo sapiens 236 EZH1   Affinity Capture-RNA Homo sapiens 237 ATF1   Affinity Capture-RNA Homo sapiens 238 NIFK 84365 Affinity Capture-MS Homo sapiens 239 CDK1 983 Affinity Capture-RNA Homo sapiens 240 NTNG2   Affinity Capture-RNA Homo sapiens 241 DYNC1H1 1778 Affinity Capture-MS Homo sapiens 242 UFL1 23376 Affinity Capture-MS Homo sapiens 243 RB1 5925 Affinity Capture-RNA Homo sapiens 244 EPHA3 2042 Affinity Capture-RNA Homo sapiens 245 RHEB 6009 Affinity Capture-RNA Homo sapiens 246 RBM4 5936 Affinity Capture-MS Homo sapiens 247 SEMA4B   Affinity Capture-RNA Homo sapiens 248 DDX3X 1654 Affinity Capture-RNA Homo sapiens 249 EZH2   Affinity Capture-MS Homo sapiens Affinity Capture-RNA Homo sapiens 250 ATP6AP1 537 Affinity Capture-RNA Homo sapiens 251 CELSR2   Affinity Capture-RNA Homo sapiens 252 PRKCA 5578 Affinity Capture-RNA Homo sapiens 253 C1orf109   Two-hybrid Homo sapiens 254 ARF1 375 Affinity Capture-RNA Homo sapiens 255 SERBP1 26135 Proximity Label-MS Homo sapiens 256 MYO6 4646 Affinity Capture-MS Homo sapiens 257 TENM3 55714 Affinity Capture-RNA Homo sapiens 258 GNB2L1 10399 Two-hybrid Homo sapiens 259 ISL2   Affinity Capture-RNA Homo sapiens 260 AP3D1 8943 Affinity Capture-RNA Homo sapiens 261 PTCH1   Affinity Capture-RNA Homo sapiens 262 DYNC2H1 79659 Affinity Capture-RNA Homo sapiens 263 RBCK1   Two-hybrid Homo sapiens 264 NDN 4692 Two-hybrid Homo sapiens 265 NOTCH1 4851 Affinity Capture-RNA Homo sapiens 266 UNC13B 10497 Affinity Capture-RNA Homo sapiens 267 KDM1A 23028 Affinity Capture-RNA Homo sapiens 268 EP300 2033 Affinity Capture-RNA Homo sapiens 269 CDC5L 988 Affinity Capture-MS Homo sapiens 270 PRKG1 5592 Affinity Capture-RNA Homo sapiens 271 CCND3   Affinity Capture-RNA Homo sapiens View the network

Pathways in which MKRN2 is involved

No pathways found