Gene description for AP3S2
Gene name
adaptor-related protein complex 3, sigma 2 subunit
Gene symbol
AP3S2
Other names/aliases
AP3S3 sigma3b
Species
Homo sapiens
Database cross references - AP3S2
ExoCarta
ExoCarta_10239
Vesiclepedia
VP_10239
Entrez Gene
10239
HGNC
571
MIM
602416
UniProt
P59780
AP3S2 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells
26054723
Gene ontology annotations for AP3S2
Experiment description of studies that identified AP3S2 in exosomes
1
Experiment ID
235
MISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Enriched markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
235
MISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Enriched markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
Protein-protein interactions for AP3S2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
AP3B1
8546
Affinity Capture-MS
Homo sapiens
Invivo
Homo sapiens
2
ARF1
375
Reconstituted Complex
Homo sapiens
3
ARF6
382
Reconstituted Complex
Homo sapiens
View the network
image/svg+xml
Pathways in which AP3S2 is involved
No pathways found