Gene description for Cntn1
Gene name contactin 1
Gene symbol Cntn1
Other names/aliases AW495098
CNTN
F3cam
Species Mus musculus
 Database cross references - Cntn1
ExoCarta ExoCarta_12805
Vesiclepedia VP_12805
Entrez Gene 12805
UniProt P12960  
 Cntn1 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Cntn1
Molecular Function
    protein binding GO:0005515 IPI
    glycoprotein binding GO:0001948 IDA
    carbohydrate binding GO:0030246 IDA
Biological Process
    cerebellum development GO:0021549 IMP
    positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 ISO
    positive regulation of gene expression GO:0010628 IMP
    positive regulation of neuron projection development GO:0010976 IGI
    positive regulation of sodium ion transport GO:0010765 IMP
    cell adhesion GO:0007155 IEA
    neuron projection development GO:0031175 IGI
    Notch signaling pathway GO:0007219 IEA
Subcellular Localization
    membrane raft GO:0045121 ISO
    myelin sheath GO:0043209 IDA
    anchored component of membrane GO:0031225 IEA
    plasma membrane GO:0005886 IEA
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 IEA
 Experiment description of studies that identified Cntn1 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Cntn1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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