Gene description for OTUD7A
Gene name OTU deubiquitinase 7A
Gene symbol OTUD7A
Other names/aliases C15orf16
Species Homo sapiens
 Database cross references - OTUD7A
ExoCarta ExoCarta_161725
Entrez Gene 161725
HGNC 20718
MIM 612024
UniProt Q8TE49  
 OTUD7A identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for OTUD7A
Molecular Function
    zinc ion binding GO:0008270 IEA
    ubiquitin-specific protease activity GO:0004843 IDA
    DNA binding GO:0003677 IEA
Biological Process
    protein K11-linked deubiquitination GO:0035871 IDA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified OTUD7A in exosomes
Experiment ID 224
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for OTUD7A
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which OTUD7A is involved
No pathways found

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