Gene description for OTUD5
Gene name	OTU deubiquitinase 5
Gene symbol	OTUD5
Other names/aliases	DUBA
Species	Homo sapiens
Database cross references - OTUD5
ExoCarta	ExoCarta_55593
Vesiclepedia	VP_55593
Entrez Gene	55593
HGNC	25402
MIM	300713
UniProt	Q96G74
OTUD5 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for OTUD5

Molecular Function     cysteine-type deubiquitinase activity GO:0004843 IBA     cysteine-type deubiquitinase activity GO:0004843 IDA     K63-linked deubiquitinase activity GO:0061578 EXP     K63-linked deubiquitinase activity GO:0061578 IBA     K63-linked deubiquitinase activity GO:0061578 IDA     K63-linked deubiquitinase activity GO:0061578 IMP     deubiquitinase activity GO:0101005 IDA     deubiquitinase activity GO:0101005 IMP     K48-linked deubiquitinase activity GO:1990380 IDA     K48-linked deubiquitinase activity GO:1990380 IMP Biological Process     proteolysis GO:0006508 IEA     neural crest cell differentiation GO:0014033 IMP     protein deubiquitination GO:0016579 IDA     protein deubiquitination GO:0016579 TAS     negative regulation of type I interferon production GO:0032480 TAS     response to lipopolysaccharide GO:0032496 IDA     regulation of immune response GO:0050776 IBA     protein K63-linked deubiquitination GO:0070536 IDA     protein K63-linked deubiquitination GO:0070536 IMP     protein K48-linked deubiquitination GO:0071108 IDA     protein K48-linked deubiquitination GO:0071108 IMP     negative regulation of canonical Wnt signaling pathway GO:0090090 IBA     negative regulation of canonical Wnt signaling pathway GO:0090090 IMP     positive regulation of TORC1 signaling GO:1904263 IBA     positive regulation of TORC1 signaling GO:1904263 IMP     positive regulation of TORC2 signaling GO:1904515 IBA     positive regulation of TORC2 signaling GO:1904515 IMP Subcellular Localization     nucleus GO:0005634 IDA     cytosol GO:0005829 TAS