Gene description for Itsn1
Gene name	intersectin 1 (SH3 domain protein 1A)
Gene symbol	Itsn1
Other names/aliases	AA517634 AA545208 AI316805 AI839402 AI848451 Ehsh1 Ese1 Itsn Sh3p17
Species	Mus musculus
Database cross references - Itsn1
ExoCarta	ExoCarta_16443
Entrez Gene	16443
UniProt	Q9Z0R4
Itsn1 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Itsn1

Molecular Function     protein complex scaffold GO:0032947 ISO     calcium ion binding GO:0005509 IEA     Rho guanyl-nucleotide exchange factor activity GO:0005089 IEA     protein binding GO:0005515 IPI     metal ion binding GO:0046872 IEA     proline-rich region binding GO:0070064 ISO     guanyl-nucleotide exchange factor activity GO:0005085 IEA     kinase activator activity GO:0019209 IDA Biological Process     positive regulation of catalytic activity GO:0043085 IDA     endocytosis GO:0006897 IEA     small GTPase mediated signal transduction GO:0007264 IDA     positive regulation of phosphorylation GO:0042327 IDA     intracellular signal transduction GO:0035556 IEA     positive regulation of protein kinase B signaling GO:0051897 IDA     negative regulation of neuron apoptotic process GO:0043524 IMP     regulation of Rho protein signal transduction GO:0035023 IEA Subcellular Localization     synapse GO:0045202 IEA     terminal bouton GO:0043195 ISO     plasma membrane GO:0005886 ISO     cell junction GO:0030054 IEA     neuron projection GO:0043005 IEA     endocytic vesicle GO:0030139 IDA     cell projection GO:0042995 IEA     coated pit GO:0005905 ISO     membrane GO:0016020 IEA     lamellipodium GO:0030027 IDA