Gene description for Mcm2
Gene name minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
Gene symbol Mcm2
Other names/aliases AA959861
AW476101
BM28
CDCL1
Mcmd2
mKIAA0030
Species Mus musculus
 Database cross references - Mcm2
ExoCarta ExoCarta_17216
Entrez Gene 17216
UniProt P97310  
 Mcm2 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Mcm2
Molecular Function
    DNA helicase activity GO:0003678 IEA
    ATP binding GO:0005524 IEA
    DNA binding GO:0003677 IEA
    metal ion binding GO:0046872 IEA
    helicase activity GO:0004386 IEA
    DNA replication origin binding GO:0003688 IDA
    histone binding GO:0042393 IDA
    hydrolase activity GO:0016787 IEA
    nucleotide binding GO:0000166 IEA
Biological Process
    nucleosome assembly GO:0006334 IDA
    DNA replication GO:0006260 IEA
    cellular response to interleukin-4 GO:0071353 IDA
    DNA unwinding involved in DNA replication GO:0006268 IDA
    DNA replication initiation GO:0006270 TAS
    cell cycle GO:0007049 IEA
Subcellular Localization
    cytoplasm GO:0005737 ISO
    microtubule cytoskeleton GO:0015630 ISO
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 ISO
    MCM complex GO:0042555 ISO
    chromatin GO:0000785 ISO
    nuclear origin of replication recognition complex GO:0005664 IDA
 Experiment description of studies that identified Mcm2 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Mcm2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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