Gene description for NQO2
Gene name NAD(P)H dehydrogenase, quinone 2
Gene symbol NQO2
Other names/aliases DHQV
Species Homo sapiens
 Database cross references - NQO2
ExoCarta ExoCarta_4835
Entrez Gene 4835
HGNC 7856
MIM 160998
UniProt P16083  
 NQO2 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for NQO2
Molecular Function
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
    electron carrier activity GO:0009055 TAS
    dihydronicotinamide riboside quinone reductase activity GO:0001512 IEA
    NADPH dehydrogenase (quinone) activity GO:0008753 TAS
Biological Process
    memory GO:0007613 IEA
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified NQO2 in exosomes
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for NQO2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GORASP2 26003
Two-hybrid Homo sapiens
2 NQO2 4835
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which NQO2 is involved
No pathways found

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