Gene description for APBB1IP
Gene name amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
Gene symbol APBB1IP
Other names/aliases INAG1
PREL1
RARP1
RIAM
Species Homo sapiens
 Database cross references - APBB1IP
ExoCarta ExoCarta_54518
Vesiclepedia VP_54518
Entrez Gene 54518
HGNC 17379
MIM 609036
UniProt Q7Z5R6  
 APBB1IP identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for APBB1IP
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell GO:0002291 IEA
    signal transduction GO:0007165 IEA
    positive regulation of cell adhesion GO:0045785 IEA
Subcellular Localization
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    cytoskeleton GO:0005856 IEA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    focal adhesion GO:0005925 IEA
    lamellipodium GO:0030027 IEA
    T cell receptor complex GO:0042101 IEA
 Experiment description of studies that identified APBB1IP in exosomes
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for APBB1IP
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZDHHC17 23390
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
2 SNW1 22938
Affinity Capture-MS Homo sapiens
3 ANXA13 312
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 PACSIN2 11252
Affinity Capture-MS Homo sapiens
5 HRAS 3265
Reconstituted Complex Homo sapiens
6 GAS7  
Reconstituted Complex Homo sapiens
7 PACSIN1  
Affinity Capture-MS Homo sapiens
8 NDN 4692
Two-hybrid Homo sapiens
9 PACSIN3 29763
Affinity Capture-MS Homo sapiens
10 ACTA2 59
Affinity Capture-MS Homo sapiens
11 PLEKHH1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 PRPF40A 55660
Reconstituted Complex Homo sapiens
13 DDX58 23586
Affinity Capture-RNA Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here