Gene description for Vps29
Gene name vacuolar protein sorting 29 (S. pombe)
Gene symbol Vps29
Other names/aliases 2010015D08Rik
AW049835
PEP11
Species Mus musculus
 Database cross references - Vps29
ExoCarta ExoCarta_56433
Entrez Gene 56433
UniProt Q9QZ88  
 Vps29 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
Pancreatic cells 19351151    
 Gene ontology annotations for Vps29
Molecular Function
    metal ion binding GO:0046872 IEA
    zinc ion binding GO:0008270 IBA
    protein binding GO:0005515 IPI
    protein transporter activity GO:0008565 IBA
Biological Process
    retrograde transport, endosome to plasma membrane GO:1990126 ISO
    retrograde transport, endosome to Golgi GO:0042147 IBA
    Golgi to vacuole transport GO:0006896 ISS
    intracellular protein transport GO:0006886 IBA
    protein transport GO:0015031 IEA
    transport GO:0006810 IEA
Subcellular Localization
    cell GO:0005623 ISS
    endosome GO:0005768 ISO
    retromer complex GO:0030904 ISO
    membrane GO:0016020 IEA
    extracellular exosome GO:0070062 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    cytoplasm GO:0005737 ISO
    intracellular GO:0005622 ISS
 Experiment description of studies that identified Vps29 in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Vps29
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Vps29 is involved
PathwayEvidenceSource
WNT ligand biogenesis and trafficking IEA Reactome





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