Gene description for Vps26a
Gene name vacuolar protein sorting 26 homolog A (yeast)
Gene symbol Vps26a
Other names/aliases AA407240
HB58
Vps26
Species Mus musculus
 Database cross references - Vps26a
ExoCarta ExoCarta_30930
Entrez Gene 30930
UniProt P40336  
 Vps26a identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Vps26a
Molecular Function
    protein transporter activity GO:0008565 IBA
    protein binding GO:0005515 IPI
Biological Process
    transport GO:0006810 IEA
    intracellular protein transport GO:0006886 IBA
    protein transport GO:0015031 IEA
    retrograde transport, endosome to Golgi GO:0042147 ISO
    retrograde transport, endosome to plasma membrane GO:1990126 ISO
Subcellular Localization
    endosome GO:0005768 ISO
    vesicle GO:0031982 ISO
    extracellular exosome GO:0070062 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    cell GO:0005623 IBA
    cytoplasm GO:0005737 IEA
    intracellular GO:0005622 IBA
    membrane GO:0016020 IEA
    tubular endosome GO:0097422 ISO
    early endosome GO:0005769 ISO
    cytosol GO:0005829 ISO
    retromer complex GO:0030904 IDA
 Experiment description of studies that identified Vps26a in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Vps26a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Vps26a is involved
PathwayEvidenceSource
WNT ligand biogenesis and trafficking IEA Reactome





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