Gene description for Vps26a
Gene name vacuolar protein sorting 26 homolog A (yeast)
Gene symbol Vps26a
Other names/aliases AA407240
HB58
Vps26
Species Mus musculus
 Database cross references - Vps26a
ExoCarta ExoCarta_30930
Vesiclepedia VP_30930
Entrez Gene 30930
UniProt P40336  
 Vps26a identified in sEVs derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Vps26a
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    intracellular protein transport GO:0006886 IBA
    intracellular protein transport GO:0006886 IEA
    endocytic recycling GO:0032456 ISO
    endocytic recycling GO:0032456 ISS
    retrograde transport, endosome to Golgi GO:0042147 IBA
    retrograde transport, endosome to Golgi GO:0042147 IDA
    retrograde transport, endosome to Golgi GO:0042147 ISO
Subcellular Localization
    lysosome GO:0005764 IEA
    lysosome GO:0005764 ISO
    endosome GO:0005768 IBA
    endosome GO:0005768 IDA
    endosome GO:0005768 ISO
    early endosome GO:0005769 IDA
    early endosome GO:0005769 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    endosome membrane GO:0010008 IEA
    endosome membrane GO:0010008 ISO
    retromer complex GO:0030904 IBA
    retromer complex GO:0030904 IDA
    retromer complex GO:0030904 ISO
    retromer complex GO:0030904 TAS
    retromer, cargo-selective complex GO:0030906 IEA
    retromer, cargo-selective complex GO:0030906 ISO
    vesicle GO:0031982 ISO
    vesicle GO:0031982 ISS
    tubular endosome GO:0097422 ISO
    tubular endosome GO:0097422 ISS
 Experiment description of studies that identified Vps26a in sEVs
1
Experiment ID 188
MISEV standards
EM
Biophysical techniques
GAPDH|UCHL1|HSP90
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors "Lee HS, Jeong J, Lee KJ."
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Vps26a
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Snx2 67804
Co-fractionation Mus musculus
2 Snx27 76742
Co-fractionation Mus musculus
3 Snx5 69178
Co-fractionation Mus musculus
4 Tbc1d5  
Co-fractionation Mus musculus
5 Tars 110960
Co-fractionation Mus musculus
6 Ankfy1 11736
Co-fractionation Mus musculus
7 Rab7 19349
Co-fractionation Mus musculus
8 Vps26b  
Co-fractionation Mus musculus
9 Snx6 72183
Co-fractionation Mus musculus
10 Vps35 65114
Co-fractionation Mus musculus
11 Vps29 56433
Co-fractionation Mus musculus
12 Atg12  
Negative Genetic Mus musculus
13 Ddi2  
Co-fractionation Mus musculus
14 Snx1  
Co-fractionation Mus musculus
15 Vps26a 30930
Cross-Linking-MS (XL-MS) Mus musculus
Cross-Linking-MS (XL-MS) Mus musculus
View the network image/svg+xml
 Pathways in which Vps26a is involved
PathwayEvidenceSource
Signal Transduction IEA Reactome
Signaling by WNT IEA Reactome
WNT ligand biogenesis and trafficking IEA Reactome





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