Gene description for PBLD
Gene name phenazine biosynthesis-like protein domain containing
Gene symbol PBLD
Other names/aliases MAWBP
Species Homo sapiens
 Database cross references - PBLD
ExoCarta ExoCarta_64081
Entrez Gene 64081
HGNC 23301
MIM 612189
UniProt P30039  
 PBLD identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for PBLD
Molecular Function
    isomerase activity GO:0016853 IEA
    molecular_function GO:0003674 ND
    protein binding GO:0005515 IPI
Biological Process
    biosynthetic process GO:0009058 IEA
    negative regulation of epithelial to mesenchymal transition GO:0010719 IMP
    negative regulation of epithelial cell proliferation GO:0050680 IMP
    maintenance of gastrointestinal epithelium GO:0030277 IMP
    negative regulation of SMAD protein import into nucleus GO:0060392 IGI
    negative regulation of epithelial cell migration GO:0010633 IMP
    negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IMP
    negative regulation of pathway-restricted SMAD protein phosphorylation GO:0060394 IMP
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified PBLD in exosomes
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for PBLD
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TRIP13 9319
Two-hybrid Homo sapiens
2 STRAP 11171
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which PBLD is involved
No pathways found

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