Gene description for HPS6
Gene name Hermansky-Pudlak syndrome 6
Gene symbol HPS6
Other names/aliases -
Species Homo sapiens
 Database cross references - HPS6
ExoCarta ExoCarta_79803
Entrez Gene 79803
HGNC 18817
MIM 607522
UniProt Q86YV9  
 HPS6 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for HPS6
Molecular Function
    Rab GTPase binding GO:0017137 IPI
    GTP-dependent protein binding GO:0030742 IPI
Biological Process
    protein localization to membrane GO:0072657 IMP
    melanocyte differentiation GO:0030318 IEA
    blood coagulation GO:0007596 IEA
    organelle organization GO:0006996 IEA
Subcellular Localization
    membrane GO:0016020 IDA
    endoplasmic reticulum GO:0005783 IEA
    BLOC-2 complex GO:0031084 IPI
    early endosome membrane GO:0031901 IEA
 Experiment description of studies that identified HPS6 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HPS6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MNAT1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which HPS6 is involved
No pathways found





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