Gene description for GALNT5
Gene name polypeptide N-acetylgalactosaminyltransferase 5
Gene symbol GALNT5
Other names/aliases GALNAC-T5
GALNACT5
Species Homo sapiens
 Database cross references - GALNT5
ExoCarta ExoCarta_11227
Vesiclepedia VP_11227
Entrez Gene 11227
HGNC 4127
MIM 615129
UniProt Q7Z7M9  
 GALNT5 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for GALNT5
Molecular Function
    polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 IBA
    polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 IDA
    polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 TAS
    carbohydrate binding GO:0030246 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    glycosaminoglycan biosynthetic process GO:0006024 TAS
    protein O-linked glycosylation GO:0006493 IBA
    O-glycan processing GO:0016266 TAS
Subcellular Localization
    Golgi membrane GO:0000139 TAS
    Golgi apparatus GO:0005794 IBA
 Experiment description of studies that identified GALNT5 in sEVs
1
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for GALNT5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NRG1 3084
Affinity Capture-MS Homo sapiens
2 SFTPC  
Affinity Capture-MS Homo sapiens
3 PDGFRA 5156
Affinity Capture-MS Homo sapiens
4 BTNL2  
Affinity Capture-MS Homo sapiens
5 ISLR 3671
Affinity Capture-MS Homo sapiens
6 HLA-DRB1 3123
Affinity Capture-MS Homo sapiens
7 TMEM106A  
Affinity Capture-MS Homo sapiens
8 BRICD5  
Affinity Capture-MS Homo sapiens
9 EXT2 2132
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
10 CNTNAP3  
Affinity Capture-MS Homo sapiens
11 ASGR1 432
Affinity Capture-MS Homo sapiens
12 FBXO2 26232
Affinity Capture-MS Homo sapiens
13 C1orf54  
Affinity Capture-MS Homo sapiens
14 HLA-DRA 3122
Affinity Capture-MS Homo sapiens
15 GIF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
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