Gene description for GALNT5
Gene name polypeptide N-acetylgalactosaminyltransferase 5
Gene symbol GALNT5
Other names/aliases GALNAC-T5
GALNACT5
Species Homo sapiens
 Database cross references - GALNT5
ExoCarta ExoCarta_11227
Entrez Gene 11227
HGNC 4127
MIM 615129
UniProt Q7Z7M9  
 GALNT5 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for GALNT5
Molecular Function
    metal ion binding GO:0046872 IEA
    polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 IDA
    carbohydrate binding GO:0030246 IEA
Biological Process
    cellular protein metabolic process GO:0044267 TAS
    glycosaminoglycan biosynthetic process GO:0006024 TAS
    protein O-linked glycosylation GO:0006493 TAS
    post-translational protein modification GO:0043687 TAS
    O-glycan processing GO:0016266 TAS
Subcellular Localization
    cellular_component GO:0005575 ND
    integral component of membrane GO:0016021 IEA
    Golgi membrane GO:0000139 TAS
 Experiment description of studies that identified GALNT5 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for GALNT5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EXT2 2132
Invitro Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which GALNT5 is involved
PathwayEvidenceSource
O-linked glycosylation of mucins TAS Reactome





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