Gene description for ITGA1
Gene name	integrin, alpha 1
Gene symbol	ITGA1
Other names/aliases	CD49a VLA1
Species	Homo sapiens
Database cross references - ITGA1
ExoCarta	ExoCarta_3672
Entrez Gene	3672
HGNC	6134
MIM	192968
UniProt	P56199
ITGA1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Neuroblastoma cells	25944692
Platelets	25332113
Platelets	25332113
Platelets	25332113
Urine	19056867

Gene ontology annotations for ITGA1

Molecular Function     protein binding GO:0005515 IPI     receptor binding GO:0005102 IEA     collagen binding involved in cell-matrix adhesion GO:0098639 IMP     collagen binding GO:0005518 TAS     protein phosphatase binding GO:0019903 IPI     metal ion binding GO:0046872 IEA Biological Process     neutrophil chemotaxis GO:0030593 IEA     positive regulation of neuron apoptotic process GO:0043525 IEA     cellular extravasation GO:0045123 IEA     activation of MAPK activity GO:0000187 IEA     integrin-mediated signaling pathway GO:0007229 IEA     positive regulation of phosphoprotein phosphatase activity GO:0032516 IDA     cell-matrix adhesion GO:0007160 IMP     axon guidance GO:0007411 TAS     blood coagulation GO:0007596 TAS     muscle contraction GO:0006936 TAS     vasodilation GO:0042311 IEA     negative regulation of cell proliferation GO:0008285 IMP     extracellular matrix organization GO:0030198 TAS     negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 ISS Subcellular Localization     focal adhesion GO:0005925 IDA     perikaryon GO:0043204 IEA     membrane raft GO:0045121 IEA     extracellular exosome GO:0070062 IDA     external side of plasma membrane GO:0009897 IEA     integrin alpha1-beta1 complex GO:0034665 IDA     neuron projection GO:0043005 IEA     basal part of cell GO:0045178 IEA     cell surface GO:0009986 IDA     acrosomal vesicle GO:0001669 IEA     integrin complex GO:0008305 TAS     membrane GO:0016020 IDA     plasma membrane GO:0005886 TAS