Gene description for MSRA
Gene name methionine sulfoxide reductase A
Gene symbol MSRA
Other names/aliases PMSR
Species Homo sapiens
 Database cross references - MSRA
ExoCarta ExoCarta_4482
Entrez Gene 4482
HGNC 7377
MIM 601250
UniProt Q9UJ68  
 MSRA identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for MSRA
Molecular Function
    peptide-methionine (S)-S-oxide reductase activity GO:0008113 IEA
Biological Process
    response to oxidative stress GO:0006979 IEA
    protein repair GO:0030091 IEA
    cellular protein modification process GO:0006464 TAS
    methionine metabolic process GO:0006555 TAS
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    mitochondrion GO:0005739 IEA
    extracellular exosome GO:0070062 IDA
    cytoplasm GO:0005737 IDA
    actin cytoskeleton GO:0015629 IDA
    nucleoplasm GO:0005654 IDA
    membrane GO:0016020 IEA
 Experiment description of studies that identified MSRA in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for MSRA
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MSRA is involved
No pathways found





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