Gene description for MYL3
Gene name
myosin, light chain 3, alkali; ventricular, skeletal, slow
Gene symbol
MYL3
Other names/aliases
CMH8 MLC1SB MLC1V VLC1
Species
Homo sapiens
Database cross references - MYL3
ExoCarta
ExoCarta_4634
Vesiclepedia
VP_4634
Entrez Gene
4634
HGNC
7584
MIM
160790
UniProt
P08590
MYL3 identified in exosomes derived from the following tissue/cell type
Platelets
25332113
Platelets
25332113
Platelets
25332113
Gene ontology annotations for MYL3
Experiment description of studies that identified MYL3 in exosomes
1
Experiment ID
231
MISEV standards
✘
Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein Lipids
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
232
MISEV standards
✘
Biophysical techniques
✘
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
233
MISEV standards
✘
Biophysical techniques
✘
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for MYL3
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
SP1
Affinity Capture-MS
Homo sapiens
2
YWHAQ
10971
Affinity Capture-MS
Homo sapiens
3
IQGAP1
8826
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
4
MYH14
79784
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
5
MYH10
4628
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
6
MYO18A
399687
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
7
UBC
7316
Reconstituted Complex
Homo sapiens
8
SIK2
Affinity Capture-MS
Homo sapiens
9
MECOM
2122
Affinity Capture-MS
Homo sapiens
10
LCN1
3933
Affinity Capture-MS
Homo sapiens
11
ATG101
Two-hybrid
Homo sapiens
12
MYH9
4627
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
13
TAF6
6878
Cross-Linking-MS (XL-MS)
Homo sapiens
14
MYL4
4635
Affinity Capture-MS
Homo sapiens
15
CUL4A
8451
Affinity Capture-MS
Homo sapiens
16
FTH1
2495
Two-hybrid
Homo sapiens
17
MYC
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which MYL3 is involved