Gene description for TREM1
Gene name	triggering receptor expressed on myeloid cells 1
Gene symbol	TREM1
Other names/aliases	CD354 TREM-1
Species	Homo sapiens
Database cross references - TREM1
ExoCarta	ExoCarta_54210
Entrez Gene	54210
HGNC	17760
MIM	605085
UniProt	Q9NP99
TREM1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for TREM1

Molecular Function     scaffold protein binding GO:0097110 IPI     receptor activity GO:0004872 TAS Biological Process     activation of mitophagy in response to mitochondrial depolarization GO:0098779 IMP     positive regulation of defense response to virus by host GO:0002230 IMP     neutrophil extravasation GO:0072672 IEA     humoral immune response GO:0006959 TAS     blood coagulation GO:0007596 TAS     intracellular signal transduction GO:0035556 TAS     chemokine metabolic process GO:0050755 IEA     cytokine secretion involved in immune response GO:0002374 IEA     neutrophil mediated killing of gram-negative bacterium GO:0070945 IEA     leukocyte migration GO:0050900 TAS     innate immune response GO:0045087 TAS     neutrophil chemotaxis GO:0030593 IEA Subcellular Localization     extracellular region GO:0005576 IEA     integral component of membrane GO:0016021 IEA     intracellular GO:0005622 TAS     plasma membrane GO:0005886 TAS