Gene description for ARHGAP15
Gene name Rho GTPase activating protein 15
Gene symbol ARHGAP15
Other names/aliases BM046
Species Homo sapiens
 Database cross references - ARHGAP15
ExoCarta ExoCarta_55843
Entrez Gene 55843
HGNC 21030
MIM 610578
UniProt Q53QZ3  
 ARHGAP15 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for ARHGAP15
Molecular Function
    GTPase activator activity GO:0005096 IDA
Biological Process
    regulation of cell shape GO:0008360 IDA
    small GTPase mediated signal transduction GO:0007264 TAS
    positive regulation of GTPase activity GO:0043547 IEA
    regulation of small GTPase mediated signal transduction GO:0051056 TAS
Subcellular Localization
    membrane GO:0016020 IEA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified ARHGAP15 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ARHGAP15
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RAC1 5879
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which ARHGAP15 is involved
PathwayEvidenceSource
Rho GTPase cycle TAS Reactome





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