Gene description for PCDHGA7
Gene name protocadherin gamma subfamily A, 7
Gene symbol PCDHGA7
Other names/aliases PCDH-GAMMA-A7
Species Homo sapiens
 Database cross references - PCDHGA7
ExoCarta ExoCarta_56108
Vesiclepedia VP_56108
Entrez Gene 56108
HGNC 8705
MIM 606294
UniProt Q9Y5G6  
 PCDHGA7 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for PCDHGA7
Molecular Function
    calcium ion binding GO:0005509 IEA
Biological Process
    cell adhesion GO:0007155 IBA
    homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IEA
    nervous system development GO:0007399 IEA
Subcellular Localization
    plasma membrane GO:0005886 IBA
 Experiment description of studies that identified PCDHGA7 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for PCDHGA7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PCDHGA4  
Affinity Capture-MS Homo sapiens
2 PCDHGB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 PCDHGA6 56109
Affinity Capture-MS Homo sapiens
4 PCDHGA5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 ATF6  
Affinity Capture-MS Homo sapiens
6 PKP2 5318
Affinity Capture-MS Homo sapiens
7 DCHS1 8642
Affinity Capture-MS Homo sapiens
8 DPP6  
Affinity Capture-MS Homo sapiens
9 GAPDHS 26330
Affinity Capture-MS Homo sapiens
10 RYK 6259
Affinity Capture-MS Homo sapiens
11 ATP12A 479
Affinity Capture-MS Homo sapiens
12 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
13 PCDHGA12  
Affinity Capture-MS Homo sapiens
14 TMEM132A 54972
Affinity Capture-MS Homo sapiens
15 PTPRS 5802
Affinity Capture-MS Homo sapiens
16 SDCBP 6386
Affinity Capture-MS Homo sapiens
17 RPL23 9349
Affinity Capture-MS Homo sapiens
18 ATP2B2 491
Affinity Capture-MS Homo sapiens
19 IMPAD1 54928
Affinity Capture-MS Homo sapiens
20 PCDHGA10  
Affinity Capture-MS Homo sapiens
21 LTBP1 4052
Affinity Capture-MS Homo sapiens
22 MYC  
Affinity Capture-MS Homo sapiens
23 SLITRK3  
Affinity Capture-MS Homo sapiens
24 EPHB4 2050
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PCDHGA7 is involved
No pathways found





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