Gene description for Idh3a
Gene name isocitrate dehydrogenase 3 (NAD+) alpha
Gene symbol Idh3a
Other names/aliases 1110003P10Rik
1500012E04Rik
AA407078
AI316514
Species Mus musculus
 Database cross references - Idh3a
ExoCarta ExoCarta_67834
Entrez Gene 67834
UniProt Q9D6R2  
 Idh3a identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Idh3a
Molecular Function
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 IEA
    NAD binding GO:0051287 IEA
    magnesium ion binding GO:0000287 IEA
    oxidoreductase activity GO:0016491 IEA
    isocitrate dehydrogenase (NAD+) activity GO:0004449 ISO
    metal ion binding GO:0046872 IEA
Biological Process
    tricarboxylic acid cycle GO:0006099 ISO
    oxidation-reduction process GO:0055114 IEA
    2-oxoglutarate metabolic process GO:0006103 ISO
    isocitrate metabolic process GO:0006102 ISO
    NADH metabolic process GO:0006734 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    mitochondrion GO:0005739 ISO
    myelin sheath GO:0043209 IDA
 Experiment description of studies that identified Idh3a in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Idh3a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Idh3a is involved
PathwayEvidenceSource
Citric acid cycle (TCA cycle) IEA Reactome





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