Gene description for BTBD10
Gene name BTB (POZ) domain containing 10
Gene symbol BTBD10
Other names/aliases GMRP-1
GMRP1
Species Homo sapiens
 Database cross references - BTBD10
ExoCarta ExoCarta_84280
Entrez Gene 84280
HGNC 21445
MIM 615933
UniProt Q9BSF8  
 BTBD10 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for BTBD10
Biological Process
    type B pancreatic cell proliferation GO:0044342 ISS
    negative regulation of neuron death GO:1901215 ISS
    positive regulation of phosphorylation GO:0042327 ISS
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    nucleus GO:0005634 IDA
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified BTBD10 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for BTBD10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DLG5 9231
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which BTBD10 is involved
No pathways found





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