Gene description for CABP1
Gene name calcium binding protein 1
Gene symbol CABP1
Other names/aliases CALBRAIN
HCALB_BR
Species Homo sapiens
 Database cross references - CABP1
ExoCarta ExoCarta_9478
Vesiclepedia VP_9478
Entrez Gene 9478
HGNC 1384
MIM 605563
UniProt Q9NZU7  
 CABP1 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for CABP1
Molecular Function
    enzyme inhibitor activity GO:0004857 TAS
    calcium channel regulator activity GO:0005246 IBA
    calcium ion binding GO:0005509 IEA
    protein binding GO:0005515 IPI
    nuclear localization sequence binding GO:0008139 ISS
    calcium-dependent protein binding GO:0048306 IPI
Biological Process
    visual perception GO:0007601 ISS
    negative regulation of protein import into nucleus GO:0042308 ISS
Subcellular Localization
    Golgi membrane GO:0000139 IDA
    extracellular space GO:0005615 HDA
    cytoplasm GO:0005737 IBA
    cytoskeleton GO:0005856 IEA
    plasma membrane GO:0005886 IDA
    cell cortex GO:0005938 IEA
    postsynaptic density GO:0014069 IDA
    perinuclear region of cytoplasm GO:0048471 IEA
 Experiment description of studies that identified CABP1 in sEVs
1
Experiment ID 224
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for CABP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ITPR1 3708
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
2 ATPAF2 91647
Affinity Capture-MS Homo sapiens
3 CACNA1C  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
4 GRK5 2869
Reconstituted Complex Homo sapiens
5 PPP3R1 5534
Reconstituted Complex Homo sapiens
6 CACNA1A  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
7 NMT1 4836
Biochemical Activity Homo sapiens
8 FOS 2353
Reconstituted Complex Homo sapiens
9 USP4 7375
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 DDX58 23586
Affinity Capture-RNA Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here