Gene description for Cox4i1
Gene name
cytochrome c oxidase subunit IV isoform 1
Gene symbol
Cox4i1
Other names/aliases
AL024441 COX COX IV-1 COXIV Cox4 Cox4a IV-1
Species
Mus musculus
Database cross references - Cox4i1
ExoCarta
ExoCarta_12857
Vesiclepedia
VP_12857
Entrez Gene
12857
UniProt
P19783
Cox4i1 identified in sEVs derived from the following tissue/cell type
Melanoma cells
34957415
Melanoma cells
34957415
Gene ontology annotations for Cox4i1
Experiment description of studies that identified Cox4i1 in sEVs
1
Experiment ID
1117
MISEV standards
✘
Biophysical techniques
✔
Cd81|Icam1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
1118
MISEV standards
✘
Biophysical techniques
✔
Cd81|Icam1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Cox4i1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Sco1
Co-fractionation
Mus musculus
2
Etfdh
Cross-Linking-MS (XL-MS)
Mus musculus
3
Cox4i1
12857
Cross-Linking-MS (XL-MS)
Mus musculus
Cross-Linking-MS (XL-MS)
Mus musculus
Cross-Linking-MS (XL-MS)
Mus musculus
Cross-Linking-MS (XL-MS)
Mus musculus
4
Got2
14719
Cross-Linking-MS (XL-MS)
Mus musculus
5
Atp5j
Cross-Linking-MS (XL-MS)
Mus musculus
6
Ndufb5
Co-fractionation
Mus musculus
7
Ndufc2
Co-fractionation
Mus musculus
8
Agxt2
Cross-Linking-MS (XL-MS)
Mus musculus
9
Slc25a3
18674
Co-fractionation
Mus musculus
10
Ndufb3
Cross-Linking-MS (XL-MS)
Mus musculus
11
Cycs
13063
Cross-Linking-MS (XL-MS)
Mus musculus
12
Uqcrh
Cross-Linking-MS (XL-MS)
Mus musculus
13
Atp5f1
Co-fractionation
Mus musculus
14
Kctd13
Affinity Capture-MS
Mus musculus
15
Cox6c
Cross-Linking-MS (XL-MS)
Mus musculus
16
Cox7b
Cross-Linking-MS (XL-MS)
Mus musculus
17
Cox7c
Cross-Linking-MS (XL-MS)
Mus musculus
18
Atp5b
11947
Cross-Linking-MS (XL-MS)
Mus musculus
Cross-Linking-MS (XL-MS)
Mus musculus
19
Atp5o
28080
Cross-Linking-MS (XL-MS)
Mus musculus
20
Tmem173
Proximity Label-MS
Mus musculus
21
Atp5a1
11946
Cross-Linking-MS (XL-MS)
Mus musculus
22
Auh
Cross-Linking-MS (XL-MS)
Mus musculus
23
Sdha
66945
Cross-Linking-MS (XL-MS)
Mus musculus
Co-fractionation
Mus musculus
24
Cpt2
Cross-Linking-MS (XL-MS)
Mus musculus
25
Cox5b
12859
Cross-Linking-MS (XL-MS)
Mus musculus
Cross-Linking-MS (XL-MS)
Mus musculus
Cross-Linking-MS (XL-MS)
Mus musculus
26
Ndufb10
Co-fractionation
Mus musculus
27
Fastkd2
Cross-Linking-MS (XL-MS)
Mus musculus
28
Ndufa4
Cross-Linking-MS (XL-MS)
Mus musculus
29
Ndufs2
Co-fractionation
Mus musculus
30
Uqcr10
Co-fractionation
Mus musculus
31
Slc25a4
11739
Cross-Linking-MS (XL-MS)
Mus musculus
32
Ndufb6
Co-fractionation
Mus musculus
33
Mdh2
17448
Cross-Linking-MS (XL-MS)
Mus musculus
View the network
image/svg+xml
Pathways in which Cox4i1 is involved