Gene description for Atp5o
Gene name ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
Gene symbol Atp5o
Other names/aliases ATPO
D12Wsu28e
OSCP
Species Mus musculus
 Database cross references - Atp5o
ExoCarta ExoCarta_28080
Entrez Gene 28080
UniProt Q9DB20  
 Atp5o identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Atp5o
Molecular Function
    proton-transporting ATP synthase activity, rotational mechanism GO:0046933 IEA
    ATPase activity GO:0016887 ISO
    drug binding GO:0008144 ISO
    steroid binding GO:0005496 ISO
    protein complex binding GO:0032403 ISO
Biological Process
    ion transport GO:0006811 IEA
    ATP biosynthetic process GO:0006754 IEA
    proton transport GO:0015992 IEA
    ATP synthesis coupled proton transport GO:0015986 IEA
    transport GO:0006810 IEA
    mitochondrial ATP synthesis coupled proton transport GO:0042776 ISO
    ATP metabolic process GO:0046034 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    nucleus GO:0005634 ISO
    mitochondrial inner membrane GO:0005743 IEA
    plasma membrane GO:0005886 ISO
    mitochondrial proton-transporting ATP synthase complex GO:0005753 ISO
    membrane GO:0016020 IEA
    myelin sheath GO:0043209 IDA
    mitochondrion GO:0005739 ISO
    mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 ISO
 Experiment description of studies that identified Atp5o in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Atp5o
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Atp5o is involved
PathwayEvidenceSource
Formation of ATP by chemiosmotic coupling IEA Reactome





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