Gene description for Cs
Gene name citrate synthase
Gene symbol Cs
Other names/aliases 2610511A05Rik
9030605P22Rik
Ahl4
BB234005
Cis
Species Mus musculus
 Database cross references - Cs
ExoCarta ExoCarta_12974
Entrez Gene 12974
UniProt Q9CZU6  
 Cs identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cs
Molecular Function
    transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 IDA
    poly(A) RNA binding GO:0044822 ISO
    transferase activity GO:0016740 IEA
    citrate (Si)-synthase activity GO:0004108 ISO
Biological Process
    acetyl-CoA metabolic process GO:0006084 ISO
    oxaloacetate metabolic process GO:0006107 ISO
    carbohydrate metabolic process GO:0005975 ISO
    cellular carbohydrate metabolic process GO:0044262 IEA
    tricarboxylic acid cycle GO:0006099 ISO
    citrate metabolic process GO:0006101 ISO
Subcellular Localization
    mitochondrion GO:0005739 ISO
    extracellular exosome GO:0070062 ISO
    mitochondrial matrix GO:0005759 ISO
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Cs in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
2
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cs
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cs is involved
PathwayEvidenceSource
Citric acid cycle (TCA cycle) IEA Reactome





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