Gene description for Nnt
Gene name nicotinamide nucleotide transhydrogenase
Gene symbol Nnt
Other names/aliases 4930423F13Rik
AI323702
BB168308
Species Mus musculus
 Database cross references - Nnt
ExoCarta ExoCarta_18115
Entrez Gene 18115
 Nnt identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nnt
Molecular Function
    NAD(P)+ transhydrogenase (AB-specific) activity GO:0008750 IEA
    oxidoreductase activity GO:0016491 IEA
    NAD(P)+ transhydrogenase activity GO:0008746 IEA
    NADP binding GO:0050661 IEA
Biological Process
    oxidation-reduction process GO:0055114 IEA
    proton transport GO:0015992 IEA
    cell redox homeostasis GO:0045454 IEA
Subcellular Localization
    mitochondrion GO:0005739 IDA
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IEA
    mitochondrial inner membrane GO:0005743 IDA
 Experiment description of studies that identified Nnt in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nnt
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nnt is involved
No pathways found





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