Gene description for CTSL
Gene name	cathepsin L
Gene symbol	CTSL
Other names/aliases	CATL CTSL1 MEP
Species	Homo sapiens
Database cross references - CTSL
ExoCarta	ExoCarta_1514
Entrez Gene	1514
HGNC	2537
MIM	116880
UniProt	P07711
CTSL identified in exosomes derived from the following tissue/cell type
Keratinocytes	19530224
Keratinocytes	19530224

Gene ontology annotations for CTSL

Molecular Function     protein binding GO:0005515 IPI     collagen binding GO:0005518 IDA     histone binding GO:0042393 IDA     cysteine-type endopeptidase activity GO:0004197 IDA     fibronectin binding GO:0001968 IPI     cysteine-type peptidase activity GO:0008234 IDA     proteoglycan binding GO:0043394 IPI     serpin family protein binding GO:0097655 IPI Biological Process     proteolysis involved in cellular protein catabolic process GO:0051603 IDA     antigen processing and presentation GO:0019882 TAS     innate immune response GO:0045087 TAS     extracellular matrix organization GO:0030198 TAS     proteolysis GO:0006508 IDA     macrophage apoptotic process GO:0071888 NAS     cellular response to thyroid hormone stimulus GO:0097067 IEP     toll-like receptor signaling pathway GO:0002224 TAS     adaptive immune response GO:0002250 IEP     collagen catabolic process GO:0030574 TAS     antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 TAS     extracellular matrix disassembly GO:0022617 TAS Subcellular Localization     extracellular space GO:0005615 IDA     endolysosome lumen GO:0036021 TAS     extracellular region GO:0005576 TAS     lysosome GO:0005764 IDA     lysosomal lumen GO:0043202 TAS     extracellular exosome GO:0070062 IDA     nucleus GO:0005634 TAS