Gene description for GAGE2E
Gene name G antigen 2E
Gene symbol GAGE2E
Other names/aliases GAGE-2E
GAGE8
Species Homo sapiens
 Database cross references - GAGE2E
ExoCarta ExoCarta_26749
Vesiclepedia VP_26749
Entrez Gene 26749
HGNC 31960
MIM 300736
UniProt Q4V326  
 GAGE2E identified in exosomes derived from the following tissue/cell type
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
 Gene ontology annotations for GAGE2E
 Experiment description of studies that identified GAGE2E in exosomes
1
Experiment ID 363
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 364
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
3
Experiment ID 365
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for GAGE2E
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZNF644  
Affinity Capture-MS Homo sapiens
2 WDR46  
Affinity Capture-MS Homo sapiens
3 SPATS2  
Affinity Capture-MS Homo sapiens
4 WIZ 58525
Affinity Capture-MS Homo sapiens
5 HABP4  
Affinity Capture-MS Homo sapiens
6 PRRC2A 7916
Affinity Capture-MS Homo sapiens
7 DIDO1  
Affinity Capture-MS Homo sapiens
8 UTP11L  
Affinity Capture-MS Homo sapiens
9 PRPF38A 84950
Affinity Capture-MS Homo sapiens
10 LSM14A 26065
Affinity Capture-MS Homo sapiens
11 GMCL1P1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
12 ESF1 51575
Affinity Capture-MS Homo sapiens
13 PLEKHF2 79666
Two-hybrid Homo sapiens
14 TOP3B 8940
Affinity Capture-MS Homo sapiens
15 ZC3H4 23211
Affinity Capture-MS Homo sapiens
16 LENG1  
Affinity Capture-MS Homo sapiens
17 GAGE12G  
Affinity Capture-MS Homo sapiens
18 USP36  
Affinity Capture-MS Homo sapiens
19 EXOC3L2  
Two-hybrid Homo sapiens
20 TJP2 9414
Affinity Capture-MS Homo sapiens
21 GTF2F2 2963
Affinity Capture-MS Homo sapiens
22 MAP9 79884
Affinity Capture-MS Homo sapiens
23 EHMT2 10919
Affinity Capture-MS Homo sapiens
24 NSRP1  
Affinity Capture-MS Homo sapiens
25 EHMT1  
Affinity Capture-MS Homo sapiens
26 PSMB5 5693
Two-hybrid Homo sapiens
27 ZC3H13 23091
Affinity Capture-MS Homo sapiens
28 LSG1  
Affinity Capture-MS Homo sapiens
29 GMCL1  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
30 DDX52  
Affinity Capture-MS Homo sapiens
31 GTPBP4 23560
Affinity Capture-MS Homo sapiens
32 ZNHIT3  
Affinity Capture-MS Homo sapiens
33 ESCO2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GAGE2E is involved
No pathways found





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