Gene description for HGF
Gene name	hepatocyte growth factor (hepapoietin A; scatter factor)
Gene symbol	HGF
Other names/aliases	DFNB39 F-TCF HGFB HPTA SF
Species	Homo sapiens
Database cross references - HGF
ExoCarta	ExoCarta_3082
Entrez Gene	3082
HGNC	4893
MIM	142409
UniProt	P14210
HGF identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for HGF

Molecular Function     serine-type endopeptidase activity GO:0004252 NAS     protein binding GO:0005515 IPI     growth factor activity GO:0008083 NAS     identical protein binding GO:0042802 IPI     chemoattractant activity GO:0042056 IDA     protein heterodimerization activity GO:0046982 IEA Biological Process     mitotic nuclear division GO:0007067 NAS     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IDA     proteolysis GO:0006508 NAS     positive regulation of transcription from RNA polymerase II promoter GO:0045944 NAS     negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 IEA     blood coagulation GO:0007596 TAS     positive chemotaxis GO:0050918 IDA     hyaluronan metabolic process GO:0030212 IEA     negative regulation of release of cytochrome c from mitochondria GO:0090201 IDA     positive regulation of osteoblast differentiation GO:0045669 NAS     epithelial to mesenchymal transition GO:0001837 TAS     regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling GO:0060665 IDA     negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 IDA     positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 IDA     positive regulation of DNA biosynthetic process GO:2000573 IDA     positive regulation of neuron projection regeneration GO:0070572 IEA     positive regulation of myelination GO:0031643 IEA     organ regeneration GO:0031100 IEA     liver development GO:0001889 IEA     platelet degranulation GO:0002576 TAS     platelet activation GO:0030168 TAS     cellular response to hepatocyte growth factor stimulus GO:0035729 IDA     myoblast proliferation GO:0051450 IEA     negative regulation of hydrogen peroxide-mediated programmed cell death GO:1901299 IDA     cell chemotaxis GO:0060326 IDA     hepatocyte growth factor receptor signaling pathway GO:0048012 IDA     positive regulation of angiogenesis GO:0045766 IEA     activation of MAPK activity GO:0000187 IEA     positive regulation of cell migration GO:0030335 IDA Subcellular Localization     extracellular region GO:0005576 TAS     membrane GO:0016020 IDA     platelet alpha granule lumen GO:0031093 TAS     extracellular space GO:0005615 IEA