Gene description for FKBP7
Gene name FK506 binding protein 7
Gene symbol FKBP7
Other names/aliases FKBP23
PPIase
Species Homo sapiens
 Database cross references - FKBP7
ExoCarta ExoCarta_51661
Vesiclepedia VP_51661
Entrez Gene 51661
HGNC 3723
MIM 607062
UniProt Q9Y680  
 FKBP7 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for FKBP7
Molecular Function
    peptidyl-prolyl cis-trans isomerase activity GO:0003755 ISS
    calcium ion binding GO:0005509 IEA
    protein binding GO:0005515 IPI
    FK506 binding GO:0005528 ISS
    RNA polymerase II CTD heptapeptide repeat P3 isomerase activity GO:0140839 IEA
    RNA polymerase II CTD heptapeptide repeat P6 isomerase activity GO:0140840 IEA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IEA
Subcellular Localization
    endoplasmic reticulum GO:0005783 ISS
    endoplasmic reticulum lumen GO:0005788 IEA
 Experiment description of studies that identified FKBP7 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for FKBP7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LYZL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 LCN9  
Affinity Capture-MS Homo sapiens
3 GSTO1 9446
Co-fractionation Homo sapiens
4 ALDOC 230
Co-fractionation Homo sapiens
5 UBQLN4 56893
Two-hybrid Homo sapiens
6 SOD1 6647
Co-fractionation Homo sapiens
7 PRMT6  
Two-hybrid Homo sapiens
8 ATP5J 522
Co-fractionation Homo sapiens
9 PEX19 5824
Two-hybrid Homo sapiens
10 EFNA2  
Affinity Capture-MS Homo sapiens
11 ACOT11 26027
Affinity Capture-MS Homo sapiens
12 ERLEC1 27248
Affinity Capture-MS Homo sapiens
13 WFDC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 TKT 7086
Co-fractionation Homo sapiens
15 IRF2 3660
Two-hybrid Homo sapiens
16 KIAA1161 57462
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 HIST2H3A 333932
Cross-Linking-MS (XL-MS) Homo sapiens
18 DUT 1854
Co-fractionation Homo sapiens
19 PPA1 5464
Co-fractionation Homo sapiens
20 LOC554223  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 DEFA5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 CARHSP1 23589
Co-fractionation Homo sapiens
23 TTR 7276
Affinity Capture-MS Homo sapiens
24 CHST15 51363
Affinity Capture-MS Homo sapiens
25 ENO2 2026
Co-fractionation Homo sapiens
26 HGF 3082
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 ENO1 2023
Co-fractionation Homo sapiens
28 SPACA3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 SGTA 6449
Two-hybrid Homo sapiens
30 CST9L  
Affinity Capture-MS Homo sapiens
31 POU5F1  
Affinity Capture-RNA Homo sapiens
32 ST14 6768
Affinity Capture-MS Homo sapiens
33 FGFBP2  
Affinity Capture-MS Homo sapiens
34 P2RX2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 HINT1 3094
Co-fractionation Homo sapiens
36 IFNA21  
Affinity Capture-MS Homo sapiens
37 MMP19 4327
Affinity Capture-MS Homo sapiens
38 B3GNT8  
Affinity Capture-MS Homo sapiens
39 ALDOA 226
Co-fractionation Homo sapiens
40 C12orf57 113246
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which FKBP7 is involved
No pathways found





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