Gene description for FKBP11
Gene name FK506 binding protein 11, 19 kDa
Gene symbol FKBP11
Other names/aliases FKBP19
Species Homo sapiens
 Database cross references - FKBP11
ExoCarta ExoCarta_51303
Entrez Gene 51303
HGNC 18624
MIM 610571
UniProt Q9NYL4  
 FKBP11 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for FKBP11
Molecular Function
    FK506 binding GO:0005528 IBA
    peptidyl-prolyl cis-trans isomerase activity GO:0003755 IBA
Biological Process
    chaperone-mediated protein folding GO:0061077 IBA
    protein peptidyl-prolyl isomerization GO:0000413 IBA
Subcellular Localization
    membrane GO:0016020 IDA
    cytoplasm GO:0005737 IBA
    endoplasmic reticulum membrane GO:0005789 IBA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified FKBP11 in exosomes
1
Experiment ID 234
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for FKBP11
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FKBP11 is involved
No pathways found





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