Gene description for Fam60a
Gene name family with sequence similarity 60, member A
Gene symbol Fam60a
Other names/aliases Ppcs1
Pptcs1
Tera
Species Mus musculus
 Database cross references - Fam60a
ExoCarta ExoCarta_56306
Entrez Gene 56306
UniProt Q8C8M1  
 Fam60a identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Fam60a
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    negative regulation of cell migration GO:0030336 ISO
Subcellular Localization
    Sin3 complex GO:0016580 ISO
    nucleus GO:0005634 IEA
 Experiment description of studies that identified Fam60a in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Fam60a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fam60a is involved
No pathways found





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