Gene description for Sarnp
Gene name SAP domain containing ribonucleoprotein
Gene symbol Sarnp
Other names/aliases 1110005A23Rik
Cip29
Species Mus musculus
 Database cross references - Sarnp
ExoCarta ExoCarta_66118
Entrez Gene 66118
UniProt Q9D1J3  
 Sarnp identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Sarnp
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
    RS domain binding GO:0050733 IPI
    RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978 IDA
    protein binding GO:0005515 IPI
    RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription GO:0001078 IMP
    protein C-terminus binding GO:0008022 IPI
Biological Process
    mRNA export from nucleus GO:0006406 ISO
    transcription from RNA polymerase II promoter GO:0006366 IMP
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IMP
Subcellular Localization
    nuclear speck GO:0016607 ISO
    nucleus GO:0005634 IDA
    transcription export complex GO:0000346 ISO
    nucleoplasm GO:0005654 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
 Experiment description of studies that identified Sarnp in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Sarnp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sarnp is involved
No pathways found





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