Gene description for VSNL1
Gene name visinin-like 1
Gene symbol VSNL1
Other names/aliases HLP3
HPCAL3
HUVISL1
VILIP
VILIP-1
Species Homo sapiens
 Database cross references - VSNL1
ExoCarta ExoCarta_7447
Entrez Gene 7447
HGNC 12722
MIM 600817
UniProt P62760  
 VSNL1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for VSNL1
Molecular Function
    protein binding GO:0005515 IPI
    calcium ion binding GO:0005509 IEA
Biological Process
    calcium-mediated signaling GO:0019722 IEA
Subcellular Localization
    intracellular GO:0005622 IEA
 Experiment description of studies that identified VSNL1 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for VSNL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RCJMB04 4h19  
Reconstituted Complex 9031
2 FLJ36766  
Two-hybrid Homo sapiens
3 DTX2  
Two-hybrid Homo sapiens
4 ACTB 60
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which VSNL1 is involved
No pathways found





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