Gene description for ERMAP
Gene name erythroblast membrane-associated protein (Scianna blood group)
Gene symbol ERMAP
Other names/aliases BTN5
PRO2801
RD
SC
Species Homo sapiens
 Database cross references - ERMAP
ExoCarta ExoCarta_114625
Vesiclepedia VP_114625
Entrez Gene 114625
HGNC 15743
MIM 609017
UniProt Q96PL5  
 ERMAP identified in sEVs derived from the following tissue/cell type
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
 Gene ontology annotations for ERMAP
Molecular Function
    signaling receptor binding GO:0005102 IBA
    protein binding GO:0005515 IPI
Biological Process
    regulation of cytokine production GO:0001817 IBA
    T cell receptor signaling pathway GO:0050852 IBA
Subcellular Localization
    Golgi apparatus GO:0005794 IDA
    cytosol GO:0005829 IDA
    plasma membrane GO:0005886 IDA
    external side of plasma membrane GO:0009897 IBA
 Experiment description of studies that identified ERMAP in sEVs
1
Experiment ID 231
MISEV standards
Biophysical techniques
Alix|CD63|CD9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 232
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 233
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ERMAP
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KRTAP3-3  
Two-hybrid Homo sapiens
2 ZC3H18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 GEMIN2 8487
Affinity Capture-MS Homo sapiens
4 AP3B1 8546
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 CDC73  
Affinity Capture-MS Homo sapiens
6 DOCK4 9732
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 USP34 9736
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 SDC1 6382
Affinity Capture-MS Homo sapiens
9 UBR4 23352
Affinity Capture-MS Homo sapiens
10 AKAP11 11215
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 FAM199X 139231
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 EMD 2010
Two-hybrid Homo sapiens
13 G3BP2 9908
Affinity Capture-MS Homo sapiens
14 ELMO2 63916
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 NRD1 4898
Affinity Capture-MS Homo sapiens
16 LEMD1  
Two-hybrid Homo sapiens
17 SAR1B 51128
Affinity Capture-MS Homo sapiens
18 CWC22 57703
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 MECOM 2122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 VANGL1 81839
Affinity Capture-MS Homo sapiens
21 PRKAR1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 GPC1 2817
Affinity Capture-MS Homo sapiens
23 NADK2 133686
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which ERMAP is involved
No pathways found





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