Gene description for FBXO22
Gene name F-box protein 22
Gene symbol FBXO22
Other names/aliases FBX22
FISTC1
Species Homo sapiens
 Database cross references - FBXO22
ExoCarta ExoCarta_26263
Entrez Gene 26263
HGNC 13593
MIM 609096
UniProt Q8NEZ5  
 FBXO22 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for FBXO22
Molecular Function
    ubiquitin-protein transferase activity GO:0004842 TAS
Biological Process
    nucleocytoplasmic transport GO:0006913 IEA
    cellular response to starvation GO:0009267 IEA
    protein polyubiquitination GO:0000209 IEA
    positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 IEA
    regulation of skeletal muscle fiber development GO:0048742 IEA
    ubiquitin-dependent protein catabolic process GO:0006511 TAS
    cellular protein modification process GO:0006464 TAS
    positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process GO:2000060 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    Z disc GO:0030018 IEA
 Experiment description of studies that identified FBXO22 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FBXO22
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RBX1 9978
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FBXO22 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here