Gene description for HHIPL1
Gene name HHIP-like 1
Gene symbol HHIPL1
Other names/aliases KIAA1822
UNQ9245
Species Homo sapiens
 Database cross references - HHIPL1
ExoCarta ExoCarta_84439
Vesiclepedia VP_84439
Entrez Gene 84439
HGNC 19710
UniProt Q96JK4  
 HHIPL1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for HHIPL1
Molecular Function
    molecular_function GO:0003674 ND
    protein binding GO:0005515 IPI
Biological Process
    biological_process GO:0008150 ND
Subcellular Localization
    cellular_component GO:0005575 ND
    extracellular region GO:0005576 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified HHIPL1 in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for HHIPL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HSPA5 3309
Affinity Capture-MS Homo sapiens
2 KRTAP1-3  
Two-hybrid Homo sapiens
3 MYCBP2 23077
Affinity Capture-MS Homo sapiens
4 CTU1 90353
Affinity Capture-MS Homo sapiens
5 CCDC36  
Affinity Capture-MS Homo sapiens
6 TMEM201 199953
Affinity Capture-MS Homo sapiens
7 ACOT9 23597
Affinity Capture-MS Homo sapiens
8 SIL1 64374
Affinity Capture-MS Homo sapiens
9 SLC27A4 10999
Affinity Capture-MS Homo sapiens
10 BANP  
Two-hybrid Homo sapiens
11 ATAD3B 83858
Affinity Capture-MS Homo sapiens
12 CDK5RAP1  
Affinity Capture-MS Homo sapiens
13 FAM132B  
Affinity Capture-MS Homo sapiens
14 MYO19  
Affinity Capture-MS Homo sapiens
15 EFEMP2 30008
Two-hybrid Homo sapiens
16 COL12A1 1303
Affinity Capture-MS Homo sapiens
17 C8B 732
Affinity Capture-MS Homo sapiens
18 DDX11 1663
Affinity Capture-MS Homo sapiens
19 MYO1D 4642
Affinity Capture-MS Homo sapiens
20 ITPA 3704
Affinity Capture-MS Homo sapiens
21 DHRS4 10901
Affinity Capture-MS Homo sapiens
22 ETV3  
Affinity Capture-MS Homo sapiens
23 DYM  
Affinity Capture-MS Homo sapiens
24 CDC7  
Affinity Capture-MS Homo sapiens
25 POLRMT 5442
Affinity Capture-MS Homo sapiens
26 SCO2  
Affinity Capture-MS Homo sapiens
27 NRF1 4899
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which HHIPL1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here