Gene description for Idh2
Gene name	isocitrate dehydrogenase 2 (NADP+), mitochondrial
Gene symbol	Idh2
Other names/aliases	E430004F23 IDPm Idh-2
Species	Mus musculus
Database cross references - Idh2
ExoCarta	ExoCarta_269951
Vesiclepedia	VP_269951
Entrez Gene	269951
UniProt	P54071
Idh2 identified in sEVs derived from the following tissue/cell type
Neural stem cells	25242146
Pancreatic cells	19351151

Gene ontology annotations for Idh2

Molecular Function     magnesium ion binding GO:0000287 ISS     isocitrate dehydrogenase (NADP+) activity GO:0004450 IBA     isocitrate dehydrogenase (NADP+) activity GO:0004450 IDA     isocitrate dehydrogenase (NADP+) activity GO:0004450 ISO     isocitrate dehydrogenase (NADP+) activity GO:0004450 ISS     NAD binding GO:0051287 IEA Biological Process     glyoxylate cycle GO:0006097 IEA     tricarboxylic acid cycle GO:0006099 IEA     isocitrate metabolic process GO:0006102 ISS     2-oxoglutarate metabolic process GO:0006103 ISS     NADP metabolic process GO:0006739 IBA     NADP biosynthetic process GO:0006741 ISO     negative regulation of glial cell proliferation GO:0060253 ISO     negative regulation of glial cell migration GO:1903976 ISO     negative regulation of matrix metallopeptidase secretion GO:1904465 ISO Subcellular Localization     mitochondrion GO:0005739 HDA     mitochondrion GO:0005739 IBA     mitochondrion GO:0005739 ISO     mitochondrial inner membrane GO:0005743 HDA     peroxisome GO:0005777 IDA     cytosol GO:0005829 IDA