Gene description for Ppp1cc
Gene name protein phosphatase 1, catalytic subunit, gamma isoform
Gene symbol Ppp1cc
Other names/aliases PP-1G
PP1
dis2m1
Species Mus musculus
 Database cross references - Ppp1cc
ExoCarta ExoCarta_19047
Entrez Gene 19047
UniProt P63087  
 Ppp1cc identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ppp1cc
Molecular Function
    protein C-terminus binding GO:0008022 ISO
    protein domain specific binding GO:0019904 ISO
    protein phosphatase binding GO:0019903 ISO
    protein serine/threonine phosphatase activity GO:0004722 IMP
    protein complex binding GO:0032403 ISO
    protein phosphatase 1 binding GO:0008157 ISO
    protein N-terminus binding GO:0047485 ISO
    protein binding GO:0005515 IPI
Biological Process
    regulation of nucleocytoplasmic transport GO:0046822 IMP
    neuron differentiation GO:0030182 ISS
    protein dephosphorylation GO:0006470 ISO
Subcellular Localization
    dendritic spine GO:0043197 ISO
    mitochondrial outer membrane GO:0005741 IDA
    mitochondrion GO:0005739 IDA
 Experiment description of studies that identified Ppp1cc in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ppp1cc
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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